Wednesday, April 01, 2015

More research review for ALS

There are more associations for genetics than previously thought.  Using pooled DNA sequencing researchers found that about 1/3rd of ALS is genetically linked.

There are blood brain barrier problems with ALS and so they are looking at that:

Inhibiting the blood-brain and spinal cord barrier's drug efflux transporters improves the efficacy of ALS treatment with riluzole in a mouse model.
So how can diet improve this?

ACE Inhibitors may help
The use of angiotensin-converting enzyme inhibitors (ACEIs) was associated with a significant reduction in the risk of developing amyotrophic lateral sclerosis (ALS) in a new case-control study conducted in Taiwan
Could "Leaky Gut" be increasing microbes and cause a whole range of these diseases?  Better take probiotics.  Leaky gut diet should also help,

This is about a mechanism for a malfunctioning protein which is believed to be responsible for ALS.

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